A Level biology – Enzyme inhibition

Last updated: 17/02/2022

AQA A-Level Biology Proteins A Level biology – Enzyme inhibition

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Question 1 of 20

1. Question
Where do competitive inhibitors bind?
- The active site
- The activation site
- Region away from the active site
- Region away from the activation site
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Question 2 of 20

2. Question
Where do non-competitive inhibitors bind?
- Region away from the active site
- The active site
- The activation site
- Region away from the activation site
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Question 3 of 20

3. Question
Which of the following describes competitive inhibitors?
- They have a similar shape to that of the substrate molecules
- They bind to the enzyme away from the active site
- They cause the active site to change shape
- Increasing the concentration of substrate does not affect the rate of reaction
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Question 4 of 20

4. Question
Which of the following describes competitive inhibitors?
- They block the active site
- They are a different shape to the substrate
- Increasing the concentration of substrate does not affect the rate of reaction
- They cause the active site to change shape
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Question 5 of 20

5. Question
Which of the following describes non-competitive inhibitors?
- They cause the active site to change shape
- They have a similar shape to that of the substrate molecules
- Increasing concentration of a substrate will increase the rate of reaction
- They block the active site
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Question 6 of 20

6. Question
The effect that a competitive inhibitor has on enzyme activity depends on…
- The difference between the concentration of inhibitor and the concentration of substrate
- The concentration of the substrate
- The concentration of the inhibitor
- The difference between the concentration of inhibitor and the concentration of products
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Question 7 of 20

7. Question
Which of the following best describes competitive inhibitors
- The bind temporarily to the active site
- They bind permanently to the active site
- They bind permanently to the substrate
- They bind temporarily to the substrate
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Question 8 of 20

8. Question
In the presence of a fixed concentration of competitive inhibitor, increasing the substrate concentration will…
- Increase the reaction rate
- Decrease the reaction rate
- Have no effect on the reaction rate
- Decrease the concentration of product
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Question 9 of 20

9. Question
In the presence of a fixed concentration of substrate, increasing the concentration of competitive inhibitor will…
- Decrease the reaction rate
- Increase the reaction rate
- Have no effect on the reaction rate
- Increase the concentration of product
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Question 10 of 20

10. Question
Which of the following is a competitive inhibitor of the enzyme succinate dehydrogenase?
- Malonate
- Succinate
- Maltose
- Sucrose
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Question 11 of 20

11. Question
How do non-competitive inhibitors affect an enzyme’s active site?
- They attach at a binding site that is not the active site but alter the shape of the active site
- They attach at the active site and alter its shape
- They attach at a binding site that is not the active site and have no effect on the active site
- They bind to substrates and prevent them from binding to the active site
Correct

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Question 12 of 20

12. Question
In the presence of a fixed concentration of non-competitive inhibitor, increasing the substrate concentration will…
- Have no effect on the reaction rate
- Decrease the reaction rate
- Increase the reaction rate
- Decrease the concentration of product
Correct

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Question 13 of 20

13. Question
In the presence of a fixed concentration of non-competitive inhibitor, increasing the enzyme concentration will…
- Increase the reaction rate
- Decrease the reaction rate
- Have no effect on the reaction rate
- Decrease the concentration of product
Correct

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Question 14 of 20

14. Question
Increasing substrate concentration will decrease the effectiveness of which type of inhibitor?
- Competitive inhibitor
- Non-competitive inhibitor
- Both competitive and non-competitive inhibitors
- Neither competitive or non-competitive inhibitors
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Question 15 of 20

15. Question
Increasing enzyme concentration will decrease the effectiveness of which type of inhibitor?
- Non-competitive inhibitor
- Competitive inhibitor
- Both competitive and non-competitive inhibitors
- Neither competitive or non-competitive inhibitors
Correct

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Question 16 of 20

16. Question
Which type of inhibitor alters the shape of an enzyme’s active site?
- Non-competitive inhibitor
- Competitive inhibitor
- Both competitive and non-competitive inhibitors
- Neither competitive or non-competitive inhibitors
Correct

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Question 17 of 20

17. Question
Which type of inhibitor permanently alters the shape of an enzyme’s active site?
- Neither competitive or non-competitive inhibitors
- Competitive inhibitor
- Both competitive and non-competitive inhibitors
- Non-competitive inhibitor
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Question 18 of 20

18. Question
Which type of inhibitor decreases the concentration of product?
- Both competitive and non-competitive inhibitors
- Competitive inhibitor
- Neither competitive or non-competitive inhibitors
- Non-competitive inhibitor
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Question 19 of 20

19. Question
How could you test whether an unknown inhibitor is competitive or non-competitive?
- Increase the substrate concentration and see if it increases the reaction rate
- Measure the rate of substrate use
- Measure the rate of product formation
- Measure the enzyme concentration
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Question 20 of 20

20. Question
In the presence of unknown inhibtor, if the reaction rate increases when substrate concentration is increased, what type of inhibitor is it?
- Competitive inhibitor
- Non-competitive inhibitor
- Cannot tell from this test
- None of the above
Correct

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