DNA replication

Last updated: 23/02/2020

AQA A-Level Biology Nucleic acids are important information-carrying molecules DNA replication

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Question 1 of 20

1. Question
During semi-conservative DNA replication, once separated each strand of a DNA molecule…
- Acts as a template to which complementary free nucleotides bind by base-pairing
- Binds its partner to reform a double stranded DNA molecule
- Acts as a template to which non-complementary free nucleotides bind
- Is enzymatically broken up by DNA nuclease to provide nucleotides for DNA polymerase to make new DNA
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Question 2 of 20

2. Question
DNA polymerase forms what type of bond between nucleotides?
- Phosphodiester bond
- Glycosidic link
- Peptide bond
- Disulfide bridge
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Question 3 of 20

3. Question
During DNA replication, DNA polymerase forms phosphodiester bonds between which nucleotides?
- Adjacent nucleotides in the new DNA strand being synthesized
- Adjacent nucleotides in the template strand
- Complementary nucleotides in the two strands of DNA
- Free nucleotides waiting to be activated
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Question 4 of 20

4. Question
Which of the following is not a nucleotide?
- Cytosine
- Uridine
- Thymidine
- Adenosine
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Question 5 of 20

5. Question
Which of the following is not a base found in DNA?
- Guanosine
- Cytosine
- Adenine
- Thymine
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Question 6 of 20

6. Question
Which of the following is complementary to, and base-pairs with Thymine?
- Adenine
- Cytosine
- Guanine
- Uracil
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Question 7 of 20

7. Question
Which of the following is complementary to, and base-pairs with Guanine?
- Cytosine
- Adenine
- Thymine
- Uracil
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Question 8 of 20

8. Question
Which of the following is the correctly matched base-pairing found in a molecule of DNA?
- G:C
- G:T
- G:A
- C:T
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Question 9 of 20

9. Question
What is the term used when each strand of DNA can act as a template in replication?
- Semi-conservative
- Semi-similar
- Template-copying
- Semi-liberal
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Question 10 of 20

10. Question
Which of the following is the correctly matched base-pairing found in a molecule of DNA?
- A:T
- A:U
- A:C
- G:U
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Question 11 of 20

11. Question
During the process of semi-conservative replication, which protein is involved in the unwinding of DNA and the breaking of hydrogen bonds?
- DNA helicase
- DNA polymerase
- DNA lipase
- DNA nuclease
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Question 12 of 20

12. Question
If a sequence of bases on the template strand is ATGGGACA, which of the following will be the sequence of bases on the newly formed strand
- TACCCTGT
- TACCCAGT
- TACCCTCT
- TGTCCCTA
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Question 13 of 20

13. Question
What type of reaction joins adjacent nucleotides?
- Condensation
- Hydrolysis
- Reduction
- Oxidation
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Question 14 of 20

14. Question
Each molecule of a newly synthesized DNA contains how much of the original DNA material?
- Half
- A quarter
- Three quarters
- None
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Question 15 of 20

15. Question
During the process of semi-conservative replication, which protein is involved in the condensation reaction that joins adjacent nucleotides?
- DNA polymerase
- DNA helicase
- DNA lipase
- DNA nuclease
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Question 16 of 20

16. Question
How many DNA polymerase molecules are needed per DNA molecule?
- Two, one for each strand
- One for both strands
- Four, one for each of the template and new strands
- None
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Question 17 of 20

17. Question
After DNA replication, what is each DNA molecule composed of?
- One original and one new polynucleotide strand
- Two original polynucleotide strands
- Two new polynucleotide strands
- One new polynucleotide strand
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Question 18 of 20

18. Question
DNA replication occurs during which stage of the cell cycle?
- Interphase
- Prophase
- Telophase
- Metaphase
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Question 19 of 20

19. Question
Which of the following is not a requirement for semi-conservative replication of DNA?
- Five types of nucleotide
- The enzyme DNA polymerase
- ATP
- DNA
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Question 20 of 20

20. Question
DNA helicase unwinds two strands of DNA by…
- Breaking hydrogen bonds linking the complementary base pairs
- Breaking phosphodiester bonds in each strand
- Recruiting DNA polymerase
- Recruiting nucleotides
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