Monoclonal antibodies

Last updated: 18/02/2022

AQA A-Level Biology Cell recognition and the immune system Monoclonal antibodies

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Question 1 of 24

1. Question
The cross-link of antigen by the antibody is referred to as…
- Agglutination
- Complement fixation
- A cross-reaction
- All of these
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Question 2 of 24

2. Question
Which of these is a mosaic antigen?
- Virus
- Bacteria
- Hapten
- Protein
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Question 3 of 24

3. Question
Interleukin and interferon are the sources of…
- T cells
- B cells
- Alpha cells
- All of these
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Question 4 of 24

4. Question
The major primary B cells receptors are…
- IgD
- IgG
- IgA
- IgE
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Question 5 of 24

5. Question
Simple small molecules are…
- Poor antigens
- Rich antigens
- Moderate antigens
- Heterophilic antigens
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Question 6 of 24

6. Question
Helper T cells assist in the function of…
- B and T cells
- B cells
- T cells
- None of these
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Question 7 of 24

7. Question
The lg locus is roughly…
- Two thirds of all hybridomas
- One third of all hybridomas
- Half of all hybridomas
- One quarter of all hybridomas
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Question 8 of 24

8. Question
Which types of cells actually secrete antibodies?
- Plasma cells
- T cells
- Macrophage
- Dendritic cells
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Question 9 of 24

9. Question
Which cytokine stimulates the activity of B85 cells?
- Interleukins
- Lymphotoxins
- Exotoxins
- All of these
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Question 10 of 24

10. Question
When were monoclonal antibodies (mAbs) first generated?
- 1975
- 1971
- 1972
- 1952
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Question 11 of 24

11. Question
Who generated the first monoclonal antibodies (mAbs)?
- Kohler and Milstein
- Khorana and Korenberg
- Emil von Behring
- Beedle and Tautum
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Question 12 of 24

12. Question
Monoclonal antibodies (mAbs) are produced by…
- Hybridomas
- Lymphocytes
- Myeloma cells
- Plasma cells
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Question 13 of 24

13. Question
Monoclonal antibodies are routinely used in all of the following EXCEPT…
- The manipulation of the immune response
- The identification and epidemiological study of infectious microorganisms
- The identification of tumour antigens
- The classification of leukaemia
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Question 14 of 24

14. Question
Monoclonal antibodies (mAbs) are generated by…
- Identical B cells
- Alpha cells
- Identical B cells and alpha cells
- T cells
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Question 15 of 24

15. Question
Monoclonal antibodies (mAbs) can be produced via the…
- In-vivo method
- Ex-vivo method
- In-vitro method
- None of these
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Question 16 of 24

16. Question
Monoclonal antibodies (mAbs) are which type of antibodies?
- Artifical
- Natural
- Both artificial and natural
- None of these
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Question 17 of 24

17. Question
Murine is made from…
- Mouse protein
- Cow protein
- Human protein
- All of these
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Question 18 of 24

18. Question
Zevalin targets which antigen that is present on the surface of B lymphocytes?
- CD20
- CB30
- CD30
- CD10
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Question 19 of 24

19. Question
Blinatumomab is used to treat…
- Acute lymphocytic leukaemia
- Diabetes
- Herpes
- Small pox
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Question 20 of 24

20. Question
Monoclonal antibodies (mAbs) are injected…
- Intravenously
- Intramuscularly
- Both intramuscularly and intravenously
- None of these
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Question 21 of 24

21. Question
Avastin is a mAb which targets the protein…
- VEGF
- GFR
- EGFR
- None of these
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Question 22 of 24

22. Question
Name an ethical issue related to the use of monoclonal antibodies
- Animal right issues
- That they are used on humans
- That they are used on plants
- None of these
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Question 23 of 24

23. Question
ELISA is used to…
- Detect antibodies
- Kill germs
- Count red blood cells
- None of these
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Question 24 of 24

24. Question
Which technology is used for the production of monoclonal antibodies?
- Hybridoma technology
- Mass-culture technology
- Suspension culture
- None of these
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