A Level Biology – Cancer – Primrose Kitten

A Level Biology – Cancer

Last updated: 17/02/2022

AQA A-Level Biology All cells arise from other cells A Level Biology – Cancer

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Question 1 of 19

1. Question
What is another term for programmed cell death?
- Apoptosis
- Necrosis
- Mitosis
- Agranulocytosis
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Question 2 of 19

2. Question
What do some tumour suppressor genes code for?
- Apoptosis promoters
- Oncogenes
- Antioncogenes
- Mitosis promoters
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Question 3 of 19

3. Question
Which of the following is not linked to mammalian tumour development?
- Infection by Agrobacterium tumefaciens
- Abnormal methylation of oncogenes
- Abnormal methylation of tumour suppressor genes
- Increased oestrogen concentration
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Question 4 of 19

4. Question
What is true of a benign tumour? 1. Can metastasise 2. A cell mass 3. Can produce hormones 4. Always harmless
- 2 & 3
- 1 & 3
- 1 & 4
- 2 & 4
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Question 5 of 19

5. Question
What is true of a malignant tumour? 1. Can metastasise 2. Cell mass 3. Always harmless 4. Inhibit angiogenesis
- 1 & 2
- 3 & 4
- 1 & 3
- 2 & 4
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Question 6 of 19

6. Question
Which is the best description of cancer?
- Cancer is a group of around 200 diseases caused by damage to the genes that regulate mitosis
- Cancer is a disease caused by mitosis
- Cancer is a disease caused by mutation of the gene controllign cell division
- Cancer is a group of around 200 diseases caused by damage to the genes that regulate metastasis
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Question 7 of 19

7. Question
What is the name of the group of abnormal cells resulting from damage to the genes that control mitosis?
- A tumour
- A tissue
- An organ
- A biopsy
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Question 8 of 19

8. Question
Tumours develop as a consequence of what?
- Uncontrolled growth and division of cells
- Tightly controlled growth and division of cells
- Specialisation of stem cells into tumour cells
- Evolution of normal tissue under selection for faster growth
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Question 9 of 19

9. Question
What name is given to a gene that promotes uncontrolled mitosis?
- Oncogene
- Tumour supressor
- Promoter
- Mutant
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Question 10 of 19

10. Question
What name is given to a gene that prevents uncontrolled mitosis?
- Tumour supressor
- Oncogene
- Promoter
- Mutant
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Question 11 of 19

11. Question
When a tumour becomes cancerous it is described as being what?
- Malignant
- Benign
- Mutant
- Apoptotic
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Question 12 of 19

12. Question
Treatment of cancer often involves which of the following?
- Killing dividing cells by blocking part of the cell cycle
- Killing dividing cells using antibiotics to interupt their cell wall
- Killing dividing cells by inhibiting neurotransmitter uptake
- Killing dividing cells by limiting inflammation
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Question 13 of 19

13. Question
Which of the following is a drawback of treating tumours with drugs that disrupt the cell cycle?
- The drugs also affect normal cells
- The drugs predominantly affect tumour cells as they grow faster
- Disrupting the cell cycle prevents mitosis
- Many normal types of cell in the human body are non-dividing
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Question 14 of 19

14. Question
What is another name for the use of drugs that disrupt the cell cycle to treat cancer?
- Chemotherapy
- Radiotherapy
- Hydrotherapy
- Psychotherapy
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Question 15 of 19

15. Question
Which of the following describes a mode-of-action of chemotherapetic drugs?
- Preventing DNA replication
- Preventing lipid synthesis
- Preventing glucose uptake
- Preventing inflammation
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Question 16 of 19

16. Question
Which of the following describes a mode-of-action of chemotherapetic drugs?
- Inhibiting metaphase by interfering with spindle formation
- Inhibiting interphase by interfering with lysosome activity
- Inhibiting metaphase by interfering with spindle disintegration
- Inhibiting prophase by interfering with cytokinesis
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Question 17 of 19

17. Question
Why is hair loss frequent in patients underoing chemotherapy?
- Because cell cycle disrupting drugs also affect rapidly dividing normal cells, such as hair-producing cells
- Because cell cycle disrupting drugs also affect non-dividing normal cells, such as hair-producing cells
- Because cell cycle disrupting drugs also degrade the keratin that hair is made of
- Because of the stress of undergoing chemotherapy
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Question 18 of 19

18. Question
Why must the dose of a chemotherapy drug be carefully considered?
- Because the drugs also target normal cells
- Because the drugs are expensive and need to be spared
- Because the patient may become addicted to the drug
- To ensure that there are enough of the drugs for everyone
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Question 19 of 19

19. Question
Why must the doses of a chemotherapy drug not be given too frequently?
- Because normal cells also affected by the drug need a chance to recover
- Because tumour cells affected by the drug need a chance to recover
- In case the tumour turns out to be benign
- Because appointments in hospital are difficult to get
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